Cerebral cartography and connectomics
نویسندگان
چکیده
منابع مشابه
Cerebral cartography and connectomics.
Cerebral cartography and connectomics pursue similar goals in attempting to create maps that can inform our understanding of the structural and functional organization of the cortex. Connectome maps explicitly aim at representing the brain as a complex network, a collection of nodes and their interconnecting edges. This article reflects on some of the challenges that currently arise in the inte...
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UNLABELLED The rich variation in cytoarchitectonics of the human cortex is well known to play an important role in the differentiation of cortical information processing, with functional multimodal areas noted to display more branched, more spinous, and an overall more complex cytoarchitecture. In parallel, connectome studies have suggested that also the macroscale wiring profile of brain areas...
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One of the most specific but also challenging properties of the brain is its topographic organization into distinct modules or cortical areas. In this paper, we first review the concept of topographic organization and its historical development. Next, we provide a critical discussion of the current definition of what constitutes a cortical area, why the concept has been so central to the field ...
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Cerebral cartography can be understood in a limited, static, neuroanatomical sense. Temporal information from electrical recordings contributes information on regional interactions adding a functional dimension. Selective tagging and imaging of molecules adds biochemical contributions. Cartographic detail can also be correlated with normal or abnormal psychological or behavioural data. Modern c...
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The use of electron microscopy (EM) to describe the detailed synaptic connectivity in the retina has a rich history. Recent technological advances in serial electron microscopy (EM) have placed a complete description of the synaptic connectivity of the mammalian retina within reach. These new tools have recently been used to densely reconstruct the largest piece of a mammalian retina to date. C...
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ژورنال
عنوان ژورنال: Philosophical Transactions of the Royal Society B: Biological Sciences
سال: 2015
ISSN: 0962-8436,1471-2970
DOI: 10.1098/rstb.2014.0173